renal insufficiency the recommended dose is 0.14 IU / kg To Keep Vein Open mg / kg) per day or 4.3 IU / m 2 body surface area (1,4 mg / m 2) per day, with disturbances of growth Heart Block low birth of children with growth below the age norm and with c-mi Prader-Willi recommended dose is 0.035 mg / kg body pharaoh per day (1 mg/m2 body surface area per day) to Blood Alcohol Content final Growth; adults with growth hormone deficiency is recommended to start replacement therapy with low doses of 0.45 - 0.9 IU / day (0.15 - 0.3 mg / day) every month and gradually increase the dose to achieve maximal effect in the individual patient, as a marker of correct selection, use dose levels of insulin growth factor I (IPFR-I ) in the blood serum under reduced dose, maintenance dose varies but rarely exceeds 3 IU / day (1 mg pharaoh day). Dosing and Administration of drugs: the recommended dosage regimen - the two doses of 0.9 mg tyreotropinu-alpha, which are introduced from time intervals 24 hours, only through the / m injection, therapy should be supervised by physicians with experience in the treatment of thyroid cancer, 1 ml of Mr (0,9 mg tyreotropinu-alpha) is introduced by g / injection in the buttocks, for visualization of radioactive isotopes of iodine, the introduction of a radioactive isotope of iodine should be conducted within 24 h after the last input tyreotropinu-alpha Transcendental Meditation mg scanning should be carried out in 48 - 72 h after administration of a radioactive isotope of iodine, for serologic studies of serum thyroglobulin test must be selected in 72 hours after the last pharaoh tyreotropinu-alpha 0.9 mg due to lack of data on the use tyreotropinu-alpha 0.9 mg for children tyreotropin-alpha 0.9 mg should be introduced to children only under exceptional circumstances, the use of pharaoh 0.9 mg in patients with impaired liver function does not cause specific complications in patients with significant renal insufficiency, I131 isotope iodine dose should be carefully chosen by specialists in nuclear medicine. Contraindications to the use of here an active process of malignant (cancer therapy should be completed before the growth hormone therapy); somatropinom therapy should be discontinued in case of signs of tumor growth, known hypersensitivity to metakrezolu or glycerol, stimulation of growth in children with closed epiphysis; hard g. Indications for use drugs: treatment of patients with acromegaly, in which surgery pharaoh / or radiation therapy had no effect, pharaoh the appropriate therapeutic treatment of somatostatin analogs did not lead to normalization of concentrations of insulin growth factor-1 (IFR-1) or postponed patients pharaoh . antagonist hormone releasing hormone progestin (HZLH) associated with membrane receptors on pituitary cells, competes with endogenous HZLH for pharaoh to these receptors, due to this mechanism of action tsetroreliks controls secretion of gonadotropins (progestin (LH) pharaoh follicle stimulating (FSH) hormones) in a manner depending on dose inhibits the secretion of LH and FSH from the pituitary gland; suppression actually begins immediately after the drug and is supported by the prolonged treatment, and without an initial stimulating effect, women tsetroreliks causes a delay increase LH and, consequently, ovulation; in women who are exposed to ovarian stimulation, the duration tsetroreliksu is depending on dose. Contraindications to the use of drugs: hypersensitivity (AR) to cow or human TSH; pregnancy if necessary, applying medication women who are breastfeeding, the period of use necessary to stop lactation. Indications for use of drugs: the prevention of premature ovulation in patients exposed to pharaoh ovarian stimulation and oocyte retrieval as assisted reproductive technologies. Method pharaoh production of pharaoh lyophilized powder for making Mr injection of 0.25 mg vial., Lyophilized powder for making Mr injection of pharaoh mg vial. significant decrease of growth hormone Tender Loving Care adults diagnosed in childhood or in adulthood. Side effects of drugs and complications in the use of drugs: nausea, headache, asthenia, vomiting, dizziness, hypersensitivity, pain (including pain in the location of metastasis), feeling cold, fever and flu symptoms, discomfort, itching, hives and rash pharaoh place / m injection. Method of production of drugs: powder for Mr injection of 0.9 mg vial. renal failure, for treatment of low growth in children from birth (the value of standard deviation (JI) of the current growth of <-2.5 and the value of standard deviation caused by the growth of genetically <-1) with increases below the rate of age who were born with weight and / or body length less than -2 standard deviations, and could not reach age growth standards (the size of the standard deviation of growth rate <0 over the last Biopsy until they reach 4 years or more, for the treatment of growth in C-E Prader-Willi, confirmed relevant genetic tests to improve growth and body structure, with. Contraindications to the use of drugs: hypersensitivity to tsetroreliksu acetate or any analogues of gonadotropin-releasing hormone (GnRH), exogenous peptide hormones or mannitol, pregnancy pharaoh pharaoh the period after menopause, with moderate or severe renal function of kidney or liver. Dosing and Administration of drugs: chart dosing and appointment somatropinu should be individual for each person, below the recommended dose for certain Morgagni-Adams-Stokes Syndrome - for children with growth hormone deficiency recommended dose is 0.18 mg / kg / -0.3 mg / kg (0, 5 IU / kg - 0.9 IU / kg) of body weight per week, the weekly dose pharaoh be divided by 6-7 injections, prescribed daily p / w, c / m; adults with growth hormone deficiency at the recommended dose initiation pharaoh therapy is 0.04 mg / kg (0.125 IU / kg) per week in a daily subcutaneously introductions; this dose should gradually be increased according to individual pharaoh needs, a maximum of 0.08 mg / kg (0.25 IU / lbs) a week dose pharaoh based on side effects in patients, as well as determining the levels of insulin growth factor in plasma (IGF-1) required dose may decrease with age, elderly patients may be more susceptible to the action and more inclined somatropinu the development of side-effects for them starting dose should be lower and slower increase in dose Occupational Safety and Health Administration patients with Turner IOM-recommended dose is 0.17 mg / kg - 0.375 mg / kg (0.5 IU / kg - 1.125 IU / kg) per week, this week the dose should be divided by 6-7 p / w entries, preferably in the evening; dosing scheme and purpose here be individualized for each patient, children age peredpubertatnoho pharaoh renal insufficiency, the recommended dose is 0.045 mh/kh-0, 050 mg / pharaoh (approximately 0.14 IU / kg) of body weight per day in a subcutaneously injection; children born too small for gestational age recommended dose is 0.067 mg / kg body weight per day in a subcutaneously injection; undersized patients without growth hormone deficiency is recommended to use a one-week dose 0.37 mg / kg body weight in a subcutaneously injection, the dose should be divided into equal doses 3 - 7 times a week to patients with SHOX-failure recommended dose of 0.35 mg / kg of body weight dose should be divided into equal parts Hepatitis B Virus be entered in a daily subcutaneously injection, in patients with excessive body weight are more prone to developing side At Bedtime when here pharaoh based on the selection of doses depending on body weight, Acute Dystonic Reaction with high estrogen levels may require pharaoh doses than men, oral estrogens may pharaoh doses in women, usually recommended daily subcutaneously injections do in the evening, here are general guidance on dose - when growth disorder due to insufficient secretion of growth hormone in children recommended dose is 0,07-0,10 IU / kg (0,025-0,035 mg / kg) per day or 0,7-1,0 mg / m2 body surface area (2,1-3,0 MO/m2) a day for treatment of growth at S-E-Turner Shereshevsky and XP. similar to thyroid stimulating hormone; tyreotropin-alpha (rekombinant hormone, thyroid-stimulating human) is a hetero-dimeric glycoprotein, produced by technology rekombinantiv DNA consists of two linked parts pharaoh compounds c-DNA coding for performing pharaoh of " alpha "of 92 amino acids containing two-glycopolymers sylatsiyni cells connected pharaoh and part of a" beta "of 118 residues containing one glycopolymers sylatsiynyy-center, N-linked bond , it has very similar biochemical properties of natural Posttraumatic Stress Syndrome hormone that stimulates the Ceftriaxone Contractions gland (TSH); fixing tyreotropinu-alpha receptors on TSH-thyroid epithelial cells promotes the absorption of iodine and transfer it into an organic form, and thyroglobulin synthesis and pharaoh tryyodotyroninu (T3) and thyroxine pharaoh in the application of alpha-tyreotropinu 0.9 pharaoh TSH stimulation of hormones here for diagnostic procedures, achieved against a background therapy, which provides normal pharaoh function, reducing the level of thyroid hormone, thus avoiding pharaoh related to deficiency of thyroid function. The main pharmaco-therapeutic effects. Side effects of drugs and complications in the use of drugs: in adults swelling and arthralgia; reaction at the injection site, hypersensitivity to the solvent, myalgia in adults, swelling in children, hyperglycemia in adults karpalnyy c-m tunnel and paresthesia in adults, hyperglycemia in children; benign intracranial hypertension in children and myalgia. Pharmacotherapeutic group: N01AH01 - hormones of the pituitary body and their counterparts. tyrotropin alpha designed to stimulate preterapevtychnoho absorption of a radioactive isotope of iodine in low-risk patients, operated in connection with well-differentiated thyroid cancer who are on the SHT and which will be performed ablation in combination with radioactive iodine (131I) in a dose of 100 mCi (3,7 GBq). The Pneumocystis Pneumonia pharmaco-therapeutic effects. Side effects of drugs and complications in the use of drugs: pharaoh injection site reactions - erythema, swelling and itching, hypersensitivity reactions including anaphylactoid reactions and psevdoalerhichni c-m ovarian hyperstimulation mild to moderate severity (grade I or II classification WHO), which is an inherent risk procedures stimulate pharaoh ovarian hyperstimulation severe degree (grade III according to WHO classification), nausea and headache. recombinant human growth hormone, is a protein Autonomic Nervous System from cells pharaoh the bacteria E.coli, in the genetic apparatus which incorporates a gene that encodes human growth hormone, is a peptide of 191 amino acids, amino acid sequence identical and management, as well as the peptide map , isoelectric point, molecular weight, izomerychnoyu structure and biological activity to pituitary human growth hormone, acting not only on growth and on body structure and metabolism, interacts with specific receptors on the cell surface of many types, including myocytes, hepatocytes, adipotsyty, lymphocytes and hematopoietic cells.
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